Modern circuits often contain a mix of analog and digital circuits. To simulate such circuits efficiently and accurately a mix of analog and digital simulation techniques is required. When analog simulation algorithms are combined with digital simulation algorithms, the result is termed `mixed-mode simulation'.

Two basic methods of implementing mixed-mode simulation used in practice are the `native mode' and `glued mode' approaches. Native mode simulators implement both an analog algorithm and a digital algorithm in the same executable. Glued mode simulators actually use two simulators, one of which is analog and the other digital. This type of simulator must define an input/output protocol so that the two executables can communicate with each other effectively. The communication constraints tend to reduce the speed, and sometimes the accuracy, of the complete simulator. On the other hand, the use of a glued mode simulator allows the component models developed for the separate executables to be used without modification.

Ngspice is a native mode simulator providing both analog and event-based simulation in the same executable. The underlying algorithms of ngspice (coming from XSPICE and its Code Model Subsystem) allow use of all the standard SPICE models, provide a pre-defined collection of the most common analog and digital functions, and provide an extensible base on which to build additional models.